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Young organs may not be a fountain of youth for recipients

Jessica Hamzelou· 25 septembre 2026

Around this time last year I was attending an aging conference in Manchester, listening to a talk about fly aging, when my phone started pinging. News outlets were reporting that a hot mic had caught Russia’s and China’s leaders discussing the possibility of living forever. “With the developments o…

Résumé

Young organs and aging

Aging is a complex process where cells and tissues gradually lose function over time.

Scientists study it using tools called aging clocks, which are molecular methods to estimate the biological age of tissues or entire organisms.

Biological age measures how old a body or organ feels at a cellular level, unlike chronological age, which is simply the number of years since birth.

For example, a 70-year-old person might have the biological age of a 50-year-old if their cells are in good condition.

In 2023, Jesse Poganik at Brigham and Women’s Hospital in Boston led research to test whether young organs could reverse aging in older recipients.

The study focused on heart transplants in mice and humans, as hearts are often transplanted from younger donors to older patients.

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