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If you’re on GLP-1 drugs and plan to fast for Yom Kippur, here’s what you need to know

<name>Reed Berger-Fleishman, Associate Clinical Professor of Medicine and Surgery, University of Illinois Chicago</name> <foaf:homepage rdf:resource="https://theconversation.com/profiles/reed-berger-fleishman-2764205"/>· 16 septembre 2026

Fasting for Yom Kippur ends at nightfall with a family meal. halbergman/E+ via Getty Images Millions of people worldwide – as many as 1 in 8 adults in the U.S. – are on GLP-1 medication, such as Ozempic, Mounjaro, Wegovy and

Résumé

GLP-1 drugs overview

GLP-1 drugs, such as Ozempic, Mounjaro, Wegovy, and Zepbound, are medications used to treat diabetes or aid in weight loss.

They work by mimicking a natural gut hormone called glucagon-like peptide 1 (GLP-1), which helps lower blood sugar by triggering insulin release when levels are high.

These drugs also slow digestion, reducing appetite and aiding weight loss.

As of 2026, up to 1 in 8 adults in the U.S.

are taking GLP-1 medications, reflecting their widespread use.

Common side effects include nausea, vomiting, dizziness, constipation, and dehydration, which may worsen during fasting periods like Yom Kippur.

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