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Concept

UMAP (Uniform Manifold Approximation and Projection)

A computational tool used to project high-dimensional gene expression data into lower dimensions, revealing clusters of cell types and their developmental trajectories in a Waddington-like landscape.

Catégorie : Sciences

Articles liés (1)

How Does Life Unfold? A Landscape Metaphor Comes Into Its Own.

C.H. Waddington’s powerful image of embryonic stem cells specializing on a rolling landscape has captivated biologists since the 1950s. Experimental data is finally confirming, and complicating, his visionary ideas. The post How Does Life Unfold? A Landscape Metaphor Comes Into Its Own. first appeared on Quanta Magazine

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